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Oncogenic anaplastic lymphoma kinase (ALK) signaling. Schematic representation of different oncogenic forms of ALK (fusions, point mutations, amplification/overexpression) and downstream signaling pathways. FP, fusion protein; GR, glycine‐rich domain; LDL, low‐density lipoprotein class A domain; MAM, meprin, A‐5 protein and receptor protein tyrosine phosphatase Mu domain; PTK, protein tyrosine kinase domain; TM, transmembrane region.
