Skip to main content
. 2019 Apr 3;127(5):288–302. doi: 10.1111/apm.12940

Table 1.

Frequency of ALK mutations in neuroblastoma

Bresler et al. De Brouwer et al.
Number of neuroblastoma investigated 1596 709
Number of neuroblastoma with ALK mutations (%) 126 (8) 49 (6.9)
Number of ALK‐F1174L/V/S/I/C (% of ALK‐positive) 38 (30) 17 (34.7)
Number of ALK‐F1245C/I/L/V (% of ALK‐positive) 15 (12) 3 (6.1)
Number of ALK‐R1275L/Q (% of ALK‐positive) 54 (43) 24 (49)

ALK, anaplastic lymphoma kinase.

Percentage of ALK‐F1174, ALK‐F1245, ALK‐R1275 mutations in the neuroblastoma patient population is shown. Data from 58, 86.