Figure 1.

Future aspects of organ preservation and re‐conditioning with several possibilities to arrange preservation methods/technologies currently used clinically. Prospective randomized multicentre trials are needed to compare strategies (a–d) in regard to their effects and transplant outcomes. In addition, trials comparing (a–d) will deliver evidence if there are significant advantages/disadvantages of starting preservation using perfusion devices immediately after organ retrieval or in a back‐to‐base/hub approach following static cold storage. *Re‐Conditioning offers viability assessment of the organ, treatment of the organ with supplemental biologicals and stem cells as therapeutic agents. Pharmacological testing can be undertaken. The treatment to be applied or the drug/substance to be tested will determine if oxygenated hypothermic machine perfusion is enough or if a nearly physiological environment at 37 °C is needed.