Table 3.

Association of the genetic risk score (GRS) and weighted GRS with fasting plasma glucose in a Chinese population

Characteristic	Continuous score (P‐value)	Score quartiles (P‐value)				P trend
		Q1	Q2	Q3	Q4
GRS
Unadjusted	0.042 (<0.001)	1.00	0.101 (0.205)	0.155 (0.028)	0.210 (0.003)	0.002
Adjusteda	0.045 (<0.001)	1.00	0.103 (0.204)	0.170 (0.017)	0.233 (0.001)	<0.001
Male sex
Unadjusted	0.027 (0.152)	1.00	0.148 (0.225)	0.060 (0.583)	0.113 (0.319)	0.370
Adjusteda	0.036 (0.062)	1.00	0.177 (0.148)	0.117 (0.288)	0.152 (0.180)	0.189
Female sex
Unadjusted	0.051 (<0.001)	1.00	0.053 (0.569)	0.301 (0.003)	0.270 (0.003)	<0.001
Adjusteda	0.052 (<0.001)	1.00	0.044 (0.647)	0.291 (0.005)	0.280 (0.003)	<0.001
Weighted GRS
Unadjusted	0.040 (0.002)	1.00	−0.030 (0.687)	0.053 (0.476)	0.189 (0.011)	0.006
Adjusteda	0.044 (<0.001)	1.00	0.003 (0.964)	0.091 (0.226)	0.221 (0.003)	0.002
Male sex
Unadjusted	0.022 (0.279)	1.00	−0.178 (0.125)	−0.135 (0.244)	0.067 (0.564)	0.483
Adjusteda	0.029 (0.156)	1.00	−0.190 (0.103)	−0.084 (0.470)	0.100 (0.391)	0.261
Female sex
Unadjusted	0.050 (0.002)	1.00	0.051 (0.598)	0.154 (0.113)	0.293 (0.003)	0.001
Adjusteda	0.053 (0.002)	1.00	0.093 (0.350)	0.177 (0.074)	0.315 (0.002)	0.001

Note: Data are presented as β coefficients for increments of fasting plasma glucose.

^aAdjusted for age, sex, education, economic status, smoking, drinking, meat and poultry intake, cereal and bean intake, exercise, sedentary time, and body mass index.