Table 5.
Comparison of liver function changes at 1 year after surgery in Child B patients with hepatocellular carcinoma who received splenectomy and curative treatment (splenectomy group) or curative treatment alone (non‐splenectomy group)
| Before surgery | One year after surgery | P‐value | |
|---|---|---|---|
| Splenectomy group (n = 66) | |||
| White blood cell count, ×1012/L | 2.84 ± 1.26 | 6.15 ± 1.15 | <0.001 |
| Platelet count, ×109/L | 45.2 ± 19.8 | 155.3 ± 33.9 | <0.001 |
| Aspartate transaminase, U/L | 45.0 ± 25.1 | 31.3 ± 21.8 | <0.001 |
| Total bilirubin, μmol/L | 22.5 ± 9.2 | 18.6 ± 4.4 | <0.001 |
| Albumin, g/L | 33.2 ± 3.8 | 41.8 ± 3.9 | <0.001 |
| Prothrombin time, s | 16.3 ± 1.4 | 12.9 ± 1.1 | <0.001 |
| Presence of ascites | 60 (90.9) | 3 (4.6) | <0.001 |
| Child score | 7.2 ± 0.4 | 5.2 ± 0.5 | <0.001 |
| Child grade A | 0 (0.0) | 63 (95.4) | <0.001 |
| Non‐splenectomy group (n = 66) | |||
| White blood cell count, ×1012/L | 3.22 ± 0.65 | 3.38 ± 0.47 | 0.091 |
| Platelet count, ×109/L | 50.7 ± 13.4 | 52.4 ± 13.0 | 0.523 |
| Aspartate transaminase, U/L | 42.5 ± 17.7 | 31.3 ± 11.5 | <0.001 |
| Total bilirubin, μmol/L | 23.8 ± 15.4 | 20.1 ± 3.0 | 0.070 |
| Albumin, g/L | 33.1 ± 3.8 | 37.6 ± 3.6 | <0.001 |
| Prothrombin time, s | 16.3 ± 1.2 | 12.8 ± 1.5 | <0.001 |
| Presence of ascites | 62 (93.9) | 11 (16.7) | <0.001 |
| Child score | 7.3 ± 0.5 | 5.4 ± 0.8 | <0.001 |
| Child grade A | 0 (0.0) | 55 (83.3) | <0.001 |
Data are expressed as n (%) or mean ± standard deviation.