Table 1. MICs and FICIs of ITZ/TBF and VOR/TBF against isolates obtained from patients.
| The isolation | Drugs | MIC (μg/mL) | MICs of the combination | FICI | ||||
|---|---|---|---|---|---|---|---|---|
| ITZ | VOR | TBF | ITZ | VOR | TBF | |||
|
F. nubica (from case 1) |
ITZ/TBF | 1 | -- | 0.25 | 0.25 | -- | 0.125 | 0.75 |
| VOR/TBF | -- | 0.25 | 0.25 | -- | 0.0313 | 0.125 | 0.625 | |
|
F. pedrosoi (from case 2) |
ITZ/TBF | 1 | -- | 0.125 | 0.5 | -- | 0.0625 | 1 |
| VOR/TBF | -- | 0.25 | 0.125 | -- | 0.0625 | 0.0625 | 0.75 | |
|
F. pedrosoi (from case 3) |
ITZ/TBF | 1 | -- | 0.125 | 0.25 | -- | 0.125 | 1.25 |
| VOR/TBF | -- | 0.125 | 0.125 | -- | 0.0625 | 0.125 | 1.5 | |
|
F. monophora (from case 4) |
ITZ/TBF | 1 | -- | 0.125 | 0.25 | -- | 0.0625 | 0.75 |
| VOR/TBF | -- | 0. 5 | 0.125 | -- | 0.125 | 0.0625 | 0.75 | |
|
F. monophora (from case 5) |
ITZ/TBF | 1 | -- | 0.125 | 0.25 | -- | 0.0625 | 0.75 |
| VOR/TBF | -- | 0. 0625 | 0.125 | -- | 0.0313 | 0.0625 | 1 | |
MIC, minimal inhibitory concentration; FICI, fractional inhibitory concentration index; ITZ, itraconazole; TBF, terbinafine; VOR, voriconazole