Table 4.

Principal Study Characteristics

Study, publication year, country of origin	Description of subjects	Number of subjects, age and sex	MRI field strength Sequences Total scan time
Lee et al, 14 2018, Korea	Asymptomatic subjects undergoing health check‐up	229 subjects, mean age 52 years (range 37–73), 139 males	1.5T Whole body: coronal T1w FS (3D SPGR), coronal T2w STIR, and sagittal T2w 20 minutes, 28 s
Perkins et al,15 2018, USA	Asymptomatic subjects undergoing health check‐up	209 subjects, mean age 55 years (range 20–98), 137 males	3T Whole‐body: noncontrast, not further specified NR
Saya et al,16 2017, UK	Asymptomatic controls with no cancer history and minimal familial cancer history	44 subjects, median age 38 years (range 19–58), 17 males	1.5T Whole body: axial T1w, axial T2w FS HASTE and DWIBS, and coronal T1 VIBE NR
Ulus et al,17 2016, Turkey	Asymptomatic subjects undergoing health check‐up	118 subjects, mean age 47.4 years (range 20–81), 71 males	1.5T ‐ Whole body: coronal T2w HASTE and STIR, and axial T2w ‐ Upper abdomen: axial T1w in‐ and out‐of‐phase and DWI For 12 subjects intravenous contrast was used for lesion characterization 30 minutes (range 28–35)
Tarnoki et al,19 2015, Germany	Asymptomatic subjects undergoing health check‐up	22 subjects, mean age 47 years (±9), 18 males	3T ‐ Whole body: coronal T1w and STIR, and axial DWIBS ‐ Large extracranial arteries: contrast‐enhanced MRA NR
Cieszanowski et al,20 2014, Poland	Asymptomatic subjects undergoing health check‐up	666 subjects, mean age 46.4 years (age range 20–77), 465 males	1.5T ‐ Whole body: coronal T2w STIR ‐ Whole spine: sagittal T2w STIR ‐ Neck and trunk: Axial T2w TSE FS ‐ Brain: axial FLAIR ‐ Thorax: axial and coronal 3D T1w GE FS ‐ Abdomen: axial T2w TSE, 3D T1w GE FS, and in‐ and out‐of‐phase 50 minutes
Hegenscheid et al,21 2013 Germany	Random sample of adults	2500 subjects, mean age 53 years (range 21–88), 1229 males	1.5T ‐ Whole body: coronal TIRM, and sagittal T1w, T2w, and T2w* ‐ Brain: sagittal T2, and axial T1w, FLAIR, DWI, SWI, and 3D TOF MRA ‐ Neck: axial T1w ‐ Chest: axial T1 VIBE and T2 HASTE ‐ Abdomen: axial T2w FS, T1w FLASH FS, DWI, and T1w VIBE, and coronal 3D T2w (MRCP) ‐ Pelvis: axial PDw FS ‐ Cardiac: true FISP short axis and 2‐ and 4 chamber views, cine short axis, axial and 2‐, 3‐ and 4‐chamber views, and late enhancement ‐ Large arteries (men only): pre and postcontrast T1 FLASH ‐ Breast (women only): axial TIRM, T2w, DWI, and dynamic axial 3D T1w FLASH NR
Laible et al,11 2012, Germany	Asymptomatic subjects undergoing health check‐up	138 subjects, mean age 54 years (range 39–74), 118 males	1.5T ‐ Brain: T1w, T2w, (and DWI) ‐ Thorax: half‐Fourier RARE and VIBE ‐ Abdomen: half‐Fourier RARE and FLASH ‐ Cardiac: true FISP, myocardial perfusion (saturation‐recovery true FISP), and late enhancement ‐ Large extracranial arteries: contrast‐enhanced MRA NR
Takahara et al,22 2010, Japan	Asymptomatic subjects undergoing health check‐up	10 subjects, mean age 61.6 years (range 52–79), 5 males	1.5T Whole body: coronal T1w and T2w, and axial DWI NR
Lo et al,26 2008, Hong Kong	Asymptomatic medical doctors	132 subjects, mean age 56 years (range 38–82), 111 males	3T ‐ Brain: axial T1w and T2w ‐ Neck: axial T2w FS ‐ Thorax: axial T1w FLASH and T2w HASTE ‐ Abdomen: axial T1w FLASH, T2w HASTE, and T1w FS ‐ Pelvis: axial T1w FLASH and T2w HASTE ‐ Spine: sagittal T2 STIR ‐ Whole body: coronal T1 FLASH 13 minutes, 31 s
Baumgart et al,12 2007, Germany	Asymptomatic subjects undergoing health check‐up	1007 subjects, mean age 55 years (range 40–67), 720 males	1.5T ‐ Brain: axial pre and postcontrast T1w, axial and sag T2w, and 3D TOF MRA ‐ Large extracranial arteries: 3D contrast‐enhanced MRA ‐ Heart: standard, cine and late enhancement short and long axis views, Lungs: axial VIBE ‐ Colon: T1w colonography ‐ Prostate: T2w 60 minutes
Goehde et al,5 2005, Germany	Asymptomatic subjects undergoing health check‐up	298 subjects, mean age 49.7 years (range 31–73), 247 males	1.5T ‐ Brain: axial T1w, T2w, FLAIR, DWI and 3D TOF MRA ‐ Large extracranial arteries: 3D coronal FLASH contrast‐enhanced MRA ‐ Thorax: axial HASTE ‐ Heart: CINE (true FISP) and late enhancement short axis and 2‐ and 4 chamber views ‐ Colon: axial pre and postcontrast T1 VIBE 50 minutes

DWI: diffusion‐weighted imaging; DWIBS: diffusion‐weighted whole body imaging with background body signal suppression; FISP: fast imaging with steady state precession; FLAIR: fluid‐attenuated inversion recovery; FLASH: fast low‐angle shot; FS: fat suppression; HASTE: half‐Fourier acquired single turbo spin‐echo; MRA: magnetic resonance angiography; MRCP: magnetic resonance cholangiopancreatography; PD: proton density weighted; RARE: rapid acquisition with relaxation enhancement; SPGR: spoiled gradient‐echo; SWI: susceptibility weighted imaging; T1w: T1‐weighted; T2w: T2‐weighted; TIRM: turbo inversion recovery magnitude; TOF: time‐of‐flight; VIBE: volumetric interpolated breath‐hold examination.