Figure 6.

Dynamic changes in BALF neutrophil GM‐CSFRα and common β chain expression during LPS‐induced acute lung injury. Mice were treated with PBS or LPS (10 μg, intranasally [i.n.]) for the indicated time. The expression of GM‐CSFRα (A) or GM‐CSFRβ (B) was then determined, using flow cytometry, on neutrophils isolated from BALF, whole blood and bone marrow. Data are expressed as geometric mean fluorescent intensity. Data show single points as well as mean ± sem for each mouse group (n = 4–6). Statistical analysis was performed by 2‐way ANOVA with Bonferroni's post‐test (Significant at ***P < 0.001, **P < 0.01, *P < 0.05)