Table 1. Sample characteristics and scan parameters.
| Sample characteristic | LA ( = 17) | HA ( = 17) | pa | ||
|---|---|---|---|---|---|
| Age, years [mean(SD)] | 27.6 | (7.8) | 29.2 | (7.2) | 0.54 |
| Sex, n | nine female, eight male | eight female, nine male | 1.00 | ||
| Ethnicity, n | 17 WB | 4 BA, 1BB, 4 BC, 6 ME, 1 OE, 1 WB | <0.001 | ||
| Childhood Adversity | |||||
| CTQ [mean(SD)] | 3.8 | (5.2) | 15.3 | (16.1) | 0.01 |
| Parental loss (parental separation with loss of parental contact and/or death and/or going into foster care and/or being adopted) during childhood, n | 0 | 13 | <0.001 | ||
| Childhood sexual abuse | 0 | 6 | 0.02 | ||
| Adult Adversity | |||||
| Number of adverse life events over last 6 months [mean(SD)] | 0.5 (0.9) | 2.6 (1.9) | 0.001 | ||
| Life events score over last 6 months [mean(SD)] | 15.1 (37.0) | 72.3 (55.7) | <0.01 | ||
| Clinical Scores | |||||
| BDI [mean(SD)] | 2.7 (3.8) | 6.5 (5.6) | 0.03 | ||
| BAI [mean(SD)] | 4.8 (6.7) | 9.7 (10.2) | 0.11 | ||
| IES-6 [mean(SD)] | 1.7 (2.3) | 7.7 (7.6) | 0.01 | ||
| O-LIFE [mean(SD)] | 7.2 (6.5) | 13.1 (9.5) | 0.07 | ||
| ASI [mean(SD)] | 5.7 (5.8) | 11.6 (7.5) | 0.02 | ||
| Current Drug Usec,d | |||||
| Tobacco cigarette smokers in last 3 months (n) | three user, 14 non-users | four users, 13 non-users | 1.00 | ||
| Tobacco use in whole sample (cigarettes/day) [mean(SD)] | .4 | (1.5) | 1.7 | (3.6) | 0.19 |
| Alcohol use in last 3 months (n) | 15 users, two non-users | 14 users, three non-users | 1.00 | ||
| Alcohol use (UK alcohol units/week) [mean(SD)] | 10.2 | (9.0) | 7.0 | (8.9) | 0.30 |
| Scan parameter | |||||
| Injected dose (MBq) [mean(SD)] | 143.4 | (7.7) | 142.9 | (7.7) | 0.85 |
| Specific activity (MBq/µmol) [mean(SD)] | 35.3 | (6.7) | 41.4 | (15.4) | 0.14 |
| Whole striatal volume (mm3) [mean(SD)] | 16,842 | (5094) | 15,741 | (4,601) | 0.54 |
| Associative striatal volume (mm3) [mean(SD)] | 10,460 | (3202) | 9771 | (2885) | 0.54 |
| Limbic striatal volume (mm3) [mean(SD)] | 2005 | (610) | 1897 | (547) | 0.61 |
| Sensorimotor striatal volume (mm3) [mean(SD)] | 4375 | (1314) | 4072 | (1189) | 0.51 |
Abbreviations: ASI, Aberrant Salience Inventory; BA, black African; BAI; Beck Anxiety Inventory; BB, black British; BC, black Caribbean; BDI, Beck Depression Inventory; CTQ, Childhood Trauma Questionnaire; IES-6, Brief Impact of Events Scale;, mixed ethnicity; OE, other ethnicity; O-LIFE, Oxford-Liverpool Inventory of Feelings and Experiences; SEAT, Social Environment Assessment Tool; WB, White British.
a Independent-samples t-tests for variables with normal data distributions; Mann-Whitney U tests for variables with non-normal data distributions; χ2-tests for dichotomous variables.
bGroups were compared on a dichotomised ethnicity variable (white British vs ethnic minority).
c 1 UK alcohol unit = 10 mL (~7.88 g) alcohol.