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. 2019 Nov 12;8:e43476. doi: 10.7554/eLife.43476

Table 1. Descriptive characteristics of parents born from 1800 to 1996 who lost a child by death during their life course, and their siblings who did not lose a child, N (%).

Parents with loss Parents without loss P for difference
Total number 47 711 126 342 -
Sex
Female 25 125 (53) 63 328 (50) 3.65e-21
Male 22 586 (47) 63 014 (50)
Total number of children 276 819 531 736 -
Number of children, mean (SD) 5.80 (3.19) 4.21 (2.71) 0
Number of children
1 1775 (4) 16 012 (13) 0
2–4 17 766 (37) 64 908 (51)
5–9 21 947 (46) 39 019 (31)
10+ 6223 (13) 6403 (5)
Age at first child birth, mean (SD) 25.55 (5.09) 27.16 (6.11) 0
Age at matching*, mean (SD) 38.76 (15.39) 37.35 (14.60) 8.84e-67
Age at matching*
13–30 17 963 (38) 52 434 (42) 1.84e-70
31–50 19 980 (42) 51 348 (41)
51–75 8123 (17) 19 480 (15)
76+ 1645 (3) 3080 (2)
Age of deceased child, mean (SD) 9.44 (14.95) - -
Length of follow-up, mean (SD) 31.79 (18.36) 25.45 (18.03) 0
Age at death 70.81 (16.66) 71.80 (16.20) 1.40e-21

* Age at loss of first child for parents who lost a child; the same age for their siblings who did not lose a child or the age when the siblings became parents, whichever came later.