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. 2019 Nov 12;8:e43476. doi: 10.7554/eLife.43476

Table 2. Hazard ratios (HRs) and 95% confidence intervals (CIs) of premature mortality after loss of a child among young parents followed up to age 50, by time since loss and demographic characteristics, compared to their siblings.

We stratified by sibling groups and additionally adjusted for birth year and sex. IR, incidence rate, per 1000 person-years.

Overall Women Men
N (Crude IR) HR (95% CI) N (Crude IR) HR (95% CI) N (Crude IR) HR (95% CI)
Time since loss
0–4 years 1711 (10.2) 1.19 (1.11–1.27) 907 (10.3) 1.52 (1.35–1.71) 804 (10.0) 0.96 (0.85–1.07)
0–4 years* 1595 (9.5) 1.10 (1.03–1.18) 832 (9.4) 1.40 (1.24–1.58) 763 (9.5) 0.89 (0.80–1.01)
5–9 years 1145 (7.9) 1.13 (1.05–1.23) 508 (6.5) 1.22 (1.06–1.41) 637 (9.5) 1.02 (0.90–1.16)
10–19 years 1654 (8.2) 1.15 (1.07–1.23) 764 (6.7) 1.33 (1.18–1.50) 890 (10.0) 1.09 (0.97–1.22)
20–39 years 388 (6.2) 1.12 (0.98–1.29) 214 (5.3) 1.28 (1.03–1.59) 174 (7.9) 1.16 (0.91–1.48)
Child’s age at loss
0 3357 (8.9) 1.14 (1.08–1.20) 1672 (8.0) 1.43 (1.31–1.57) 1685 (9.9) 0.94 (0.86–1.03)
1–5 2016 (9.4) 1.16 (1.09–1.24) 964 (8.1) 1.26 (1.13–1.41) 1052 (11.0) 1.12 (1.00–1.25)
6–17 269 (6.7) 1.17 (0.99–1.38) 130 (5.6) 1.31 (0.99–1.74) 139 (8.3) 1.32 (1.00–1.73)
18+ 66 (5.4) 1.44 (1.05–1.97) 22 (2.8) 0.96 (0.54–1.71) 44 (10.3) 1.99 (1.24–3.20)
Number of alive children at loss
0 2390 (9.7) 1.20 (1.13–1.28) 1135 (8.3) 1.39 (1.24–1.56) 1255 (11.4) 1.15 (1.04–1.28)
1–3 2793 (8.4) 1.12 (1.06–1.18) 1379 (7.5) 1.37 (1.25–1.51) 1414 (9.5) 0.98 (0.89–1.07)
4+ 525 (8.1) 1.12 (0.99–1.26) 274 (7.3) 1.18 (0.97–1.44) 251 (9.1) 0.94 (0.77–1.14)
Sex of the lost child
Female 3075 (8.6) 1.14 (1.08–1.20) 1483 (7.5) 1.29 (1.17–1.41) 1592 (10.0) 1.06 (0.97–1.16)
Male 2633 (9.2) 1.17 (1.10–1.24) 1305 (8.2) 1.44 (1.30–1.59) 1328 (10.4) 1.01 (0.92–1.11)
Age at loss
13–30 3459 (8.5) 1.13 (1.08–1.19) 1815 (7.5) 1.33 (1.22–1.45) 1644 (10.1) 1.02 (0.93–1.12)
31–40 1945 (9.5) 1.19 (1.12–1.27) 873 (8.7) 1.43 (1.27–1.61) 1072 (10.2) 1.04 (0.93–1.15)
41–50 304 (8.7) 1.14 (0.98–1.32) 100 (6.1) 1.11 (0.81–1.52) 204 (11.0) 1.12 (0.90–1.40)
Age at first childbirth
13–21 988 (6.0) 1.20 (1.09–1.32) 653 (5.4) 1.29 (1.13–1.47) 335 (7.7) 1.15 (0.95–1.40)
22–24 1507 (8.5) 1.09 (1.01–1.17) 829 (8.0) 1.27 (1.12–1.44) 678 (9.2) 0.97 (0.84–1.11)
25–27 1520 (10.3) 1.20 (1.11–1.30) 665 (9.5) 1.35 (1.17–1.56) 855 (11.1) 1.08 (0.96–1.23)
28+ 1693 (10.8) 1.16 (1.08–1.24) 641 (9.9) 1.55 (1.34–1.80) 1052 (11.3) 1.01 (0.91–1.13)

* A sensitivity analysis excluding parents dying on the same day as their child.