Video 5. DNA co-localizes with tagged histones through mitosis and during a GLM.

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DOI: 10.7554/eLife.50778.012

Cells expressing Htb2:mCherry were stained with Hoechst 3342, a live DNA stain. The first part of the video shows an overlay of red (Htb2:mCherry) and blue (Hoechst 3342), and the second shows the channels separated. Cell 1: In a normal cell cycle, the histones co-localize with the DNA, and both increase or decrease in fluorescence in the mother cell simultaneously. Cell 2: During a GLM the histones co-localize with the DNA, and both increase or decrease in fluorescence in the mother cell simultaneously.