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. 2018 Nov 3;59(5):e629–e642. doi: 10.1093/geront/gny137

Table 2.

Characteristics and Results of Reviewed Studies

Authors Country
/region of interest
Care recipient Definition of informal care Sample characteristics of caregivers Health measure Methods Lechner (2009) matching procedure used Results (if applicable subgroup for which effect is found)
Brenna and Di Novi (2016) Europe Parent Providing assistance to a parent, step-parent, or parent-in-law at least on a weekly basis
Distinction: Intensive informal care (excludes caregivers helping with domestic chores)
Women aged 50–75 Depression (Euro-D) PSM Yes ↑ Euro-D (Southern Europeans)
larger effect when providing intensive informal care
Coe and Van Houtven (2009) US Parent Spent at least 100 hr since previous wave/in the last 2 years on helping parents/mother/ father
with basic personal activities like dressing, eating, and bathing
Men and women aged 50–64, with only a mother alive Mental health (CES-D 8); physical health (self-assessed health (SAH), diagnosed heart condition and blood pressure) Simultaneous equation models (2SLS, Arellano-Bond) N/A Continued caregiving:
↑ CES-D 8 (married males and females)
↑ Heart condition (single males)
↓ SAH (married females)
↑ SAH (married males)
Effects after 2 years:
↑ CES-D 8 (married females)
↑ Heart condition (single males)
Initial caregiving:
↑ CES-D 8 (married females)
Di Novi, Jacobs, and Migheli (2015) Europe Parent Women providing care to elderly parents living in or outside the household in the past 12 months almost weekly or almost daily Women, aged 50–65 having a parent with bad or very bad health Self-assessed health; quality of life (CASP-12) PSM Yes ↑ SAH (North and Continental European caregivers)
↓ CASP-12 (Continental European caregivers)
↑ self-realized and pleasure in life (caregivers in Continental and Mediterranean Europe)
↓ able to control life and autonomous (caregivers from Continental Europe)
Do, Norton, Stearns, and Van Houtven (2015) South Korea Parent (in-law) Any informal care provided to parents-in-law Women with living parent (in-law) aged 45+ Pain affecting daily activities; fair or poor self-rated health;
any outpatient care use; OOP spending for outpatient care; any prescription drug use; OOP spending prescription drugs
Simultaneous equation models
(2SLS, IV-probit)
N/A ↑ Pain affecting daily activities, health self-rated as poor, OOP outpatient care (daughters and daughters-in-law)
↑ Any outpatient care use, any prescription drug use (daughters)
Fukahori, Sakai, and Sato (2015) Japan Family member living in the same household A family member in the same household who is in need of care Males and their spouses aged 50–64 Employment rate, working hours, self-reported health, satisfaction with leisure time and life PSM No ↓ Likelihood of participating in work
No impact on SAH or life satisfaction (results not presented in article, mentioned in text)
Goren, Montgomery, Kahle-Wrobleski, Nakamura, and Ueda (2016) Japan Adult relatives with Alzheimer’s disease or dementia Persons currently caring for an adult relative, with Alzheimer’s disease or dementia Men and women aged 18+ Comorbidities; depression (PHQ-9); work productivity (WPAI); SF-36 PCS and MCS; health care resource utilization PSM No ↑ PHQ-9, MDD
↓ SF-36 PCS, MCS and health utilities
↑ Depression, insomnia, anxiety, and pain
↑ Absenteeism, overall work impairment, and activity impairment
↑ Emergency room and traditional provider visits in the past 6 months
Heger (2017) Europe Parent Any caregiving activities to parent (help with personal care and practical household help provided outside or inside the household)
Distinction: daily, weekly and any frequency of caregiving
Men and women aged 50–70 Depression (EURO-D); indicator whether someone suffers from ≥4 depressive symptoms Simultaneous equation models N/A ↑ Euro-D, 4+ depressive symptoms (females)
larger effect when more intensive informal care
Hernandez and Bigatti (2010) US Individual with Alzheimer’s disease or a physical disability Caring for an individual with Alzheimer’s disease or a physical disability within the past year Hispanic Americans aged 65+ Depression (CES-D 20) Direct matching No ↑ CES-D 20
Hong, Han, Reistetter, and Simpson (2016) South Korea Spouse with dementia Persons living with a spouse with dementia Men and women aged 19+ Physician-diagnosed stroke PSM No ↑ Odds of stroke
Kenny, King, and Hall (2014) Australia Spouse, adult relative, elderly parent (in law) Any time spent caring for a disabled spouse, adult relative or elderly parent/parent-in-law in a typical week
Distinction:
Care burden:
Low (less than 5 hr/w), moderate (5–19 hr/w) and high (20 or more hr/w)
16+ males and females SF-36 PCS and MCS PSM Yes After 2 years:
↑ PCS (high care)
Effects for subgroups:
↓ PCS (high caregiving females with a job)
↓ MCS (high caregiving females with a job)
↑ MCS (high caregiving males without job)
After 4 years:
↓ PCS (low and moderate care)
↓ MCS (moderate and high care)
Rosso and colleagues (2015) US Family member or friend Currently helping ≥1 sick, limited, or frail family member, or friend on a regular basis?
Distinction:
Low frequency ≤2 times per week; high frequency ≥3 times per week
Women, 65–80 years old Walking speed, grip strength, chair stands PSM No After 6 years:
↑ grip strength (low-frequency caregivers)
Schmitz and Westphal (2015) Germany Unknown Providing ≥2 hr per day on care and support for persons in need of care on a typical weekday Women aged 18+ SF-12v2 MCS and PCS PSM Yes Short term:
↓ MCS
Longer term:
No effects
Stroka (2014) Germany Anyone in need Self-reported informal caregiving to sickness fund to receive allowance
Distinction:
Level of care needed
Males and females aged 35+ Drug intake PSM + D-in-D Yes ↑ Intake of antidepressants, tranquilizers, analgesics and gastrointestinal agents
Larger effect when more intensive care
Trivedi and colleagues (2014) US Family member or friend Any care provision in the past month to a friend or family member who has a health problem, long-term illness, or disability Noninstitutionalized U.S. civilian population aged ≥18 years Self-assessed mental health; general health; perceived social and emotional support; sleep hygiene PSM No ↑ Report >15 days of poor mental health and inadequate emotional support;
↓ Report fair or poor health (females)
↑ Report fair or poor health (males)
↓ Receive recommended amount of sleep
↑ Fall asleep unintentionally during the day
de Zwart and colleagues (2017) Europe Partner Daily or almost daily caregiving activities (help with personal care) to partner for ≥3 months in the past 12 months Males and females aged 50+ Prescription drugs usage; the number of doctor visits in the past 12 months; EURO-D depression scale; self-perceived health PSM Yes Short term:
↑ Euro-D, ↓ self-reported health; ↑ prescription drug use(females), ↑ doctor visits (females)
Longer- term:
No effect

Note: PSM = propensity score matching; 2SLS = two-stage least square; D-in-D = difference-in-difference; IV = instrumental variable; MCS and PCS = Mental Component Scale and Physical Component Scale.