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NaBu inhibited Ang II‐induced activation of COX2/PGE2 pathway along with its downstream signal cascade. A, Representative immunoblots of COX2, EP4 and pERK protein levels in hearts and summarized intensities of blots. B, mRNA level of COX2 in hearts. C, ELISA analysis of cardiac PGE2 content. D, ELISA analysis of cardiac cAMP content. N = 6 per group
