Figure 2.

A, Representative images of AA in each group were presented. B, The maximum aortic diameter at the infra‐diaphragm was measured. BM‐MSCs and MSCs‐CM group showed reduced aortic diameter comparing with control medium group. C, Elastin structure of aortic wall was evaluated in each group using EVG staining. Elastin degradation was prevented in both BM‐MSCs and MSC‐CM group comparing with control medium group. D, Elastin volume of aortic wall was further evaluated in each group. Elastin volume of both BM‐MSCs and MSC‐CM group was higher than that of control medium group. E, F, mRNA expressions of MMP2 and MMP9 were determined using real‐time PCR. Fold changes were calculated and statistically analysed. MMP2 expression was significantly decreased in both BM‐MSC and MSCs‐CM group compared with control medium group; however, MMP9 expression was slightly decreased in both BM‐MSC and MSCs‐CM group