Table 1.
Study 1 and study 2 patient characteristics and antihypertensive medications
| Study 1 | Study 2 | |
|---|---|---|
| Characteristics | ||
| Age, yr | 53 ± 12 | 49 ± 13 |
| Sex, men/women | 10/3 | 11/3 |
| Height, cm | 176 ± 7 | 176 ± 7 |
| Mass, kg | 80 ± 18 | 85 ± 20 |
| Body mass index, kg/m2 | 26 ± 4 | 27 ± 5 |
| Glucose, mg/dL | 83 ± 14 | 88 ± 23 |
| Sodium, mmol/L | 142 ± 2 | 142 ± 2 |
| Potassium, mmol/L | 4.0 ± 0.4 | 4.0 ± 0.4 |
| Chloride, mmol/L | 105 ± 2 | 105 ± 3 |
| Calcium, mg/dL | 9.5 ± 0.3 | 9.4 ± 0.4 |
| Creatinine, mg/dL | 0.9 ± 0.1 | 0.9 ± 0.1 |
| Total cholesterol, mg/dL | 188 ± 31 | 185 ± 36 |
| Triglycerides, mg/dL | 141 ± 64 | 125 ± 69 |
| HDL, mg/dL | 53 ± 15 | 52 ± 16 |
| LDL, mg/dL | 116 ± 30 | 117 ± 36 |
| Hemoglobin, g/dL | 15.5 ± 0.5 | 15.6 ± 0.6 |
| Hematocrit, % | 46 ± 2 | 48 ± 9 |
| Antihypertensive medications | ||
| ACEi or ARB | 10 (77) | 9 (64) |
| Beta receptor blocker | 2 (15) | 2 (14) |
| Calcium channel blockers | 2 (15) | 2 (14) |
| Diuretic | 5 (38) | 4 (29) |
| No therapy | 0 (0) | 2 (14) |
| Monotherapy | 10 (77) | 8 (57) |
| Dual therapy | 3 (23) | 4 (29) |
Data are means ± SD. Antihypertensive medications are presented as n (% of group). Patients were studied after a 2-wk washout from antihypertensive medications. ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; HDL, high-density lipoprotein; LDL, low-density lipoprotein.