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. 2019 Nov 26;11(11):957–967. doi: 10.4252/wjsc.v11.i11.957

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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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The expression of genes for pro-inflammatory molecules in stimulated retinal explants and suppression of the gene expression by MSCs. Retinal explants were cultured for 48 h untreated (-), stimulated with IL-lα, IFN-γ and TNF-α (Cyt.) or stimulated with the cytokines in cultures containing MSCs (3 × 10⁴ in 1 mL). The expression of genes for IL-lα, IL-6 and iNOS in retinal explants was determined by real-time PCR. MSC: Mesenchymal stem cell; IL-6: Interleukin-6; IL-lα: Interleukin-lα; iNOS: Inducible nitrox oxide synthase; MSC: Mesenchymal stem cell.