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Participants were categorized intro clinical groups according to the McDonald criteria (9), (RRMS: 156, SPMS: 15, PPMS: 6, CIS: 6).
| Disease type | Age (at MS onset) | Age (at BL MRI) | Age (at last MRI) | Female/ male |
|---|---|---|---|---|
| CIS | 31 (27–39) | 30 (27–37) | 31.5 (28–38) | 6/0 |
| RRMS | 27 (20–36) | 32 (22–39) | 34 (26.5–43) | 104/52 |
| SPMS | 31.5 (23–42) | 46 (41–51) | 49 (44–58) | 11/4 |
| PPMS | 31 (28–33) | 35 (32–38) | 43 (35–44) | 3/3 |
Gender, age, age at MRI and disease duration were available for the entire cohort.
