Figure 6.

Hair regrowth in DKO and WT mice on vitamin A–deficient diet (A) and on chow diet (B). A, DKO2 and their littermate female mice were shaved at P25 (#29) and P50 (#4) after birth and photographed at P29 (4 days of hair growth) and P56 (6 days of hair growth), respectively. Shown are representative images of two sets of younger females and two sets of older females on VAD diet. DKO2 and their littermate male mice were shaved at P25 (#9) and P49 (#38) and photographed at P32 (7 days of hair growth) and P62 (13 days of hair growth), respectively. Shown are representative images of four sets of younger males and three sets of older males on VAD diet. B, female DKO1 and its WT female littermate were shaved at P25 and photographed at P30 (5 days of hair growth). Shown are representative images of six sets of females on chow diet. Male DKO1 and its WT male littermate were shaved at P49 and photographed at P60 (11 days of hair growth). Shown are representative images of four sets of males on chow diet. Images are available for additional shaved single animals from DKO1 and DKO2 strains that did not have WT littermates. The two independent strains showed a very similar external phenotype on vitamin A–deficient diet and on chow diet.