Figure 3.

Structural overview of C-terminal MUC5B. A, the composite map (from Fig. 2C) is shown with docked models of each domain. A dimer of the D4 domain fits within the base, with the monomers colored red and blue. In the stalk, the B-C-CK domains are fitted twisting along the stalk axis, with each monomer colored orange and blue. B, a surface rendered representation of the docked models shown in A with each monomer chain color coded either red or blue. C, a representative 2D class of CT5B showing this twist along the length of the stalk.