Table 2.
Correlation of WT1-mRNA expression and hematologic parameters
| WBC (x109/L) | Hb (g/dl) | PLT (×109/L) | PB blast count (%) | BM blast count (%) | Age (years) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT1 < 50* | 3.85 (0.7–17) | 0.0345 | 9.8 (4.8–14.8) | 0.4616 | 103 (9–540) | 0.0425 | 0 (0–5) | 0.0025 | 3 (0–17) | 0.0013 | 63.5 (45–84) | 0.0089 |
| WT1 > 50* | 2.7 (0.7–26) | 9.3 (6–13) | 67 (6–670) | 0 (0–11) | 6 (1–18) | 59 (22–77) |
| Gender (female/male) | Karyotype (normal/abnormal) | Karyotype (normal/komplex) | PB blasts (presence/absence) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT1 < 50a | 12 | 28 | 0.3923 | 23 | 16 | 0.0198 | 23 | 5 | 0.0296 | 1 | 37 | 0.0023 |
| WT1 > 50a | 21 | 33 | 18 | 36 | 18 | 15 | 13 | 34 | ||||
aCopies/104 ABL copies; values are presented as medians with ranges
p-value < 0.05 was considered to be statistically significant
No. number, WBC white blood cell count, Hb hemoglobin, PLT platelet count, PB peripheral blood, BM bone marrow