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. 2019 Aug 14;138(6):1075–1089. doi: 10.1007/s00401-019-02056-2

Fig. 2.

Fig. 2

Histological features of SP-EPN-MYCN Highly cellular neuroectodermal tumor with a perivascular pseudorosettes, b microvascular proliferation, c perivascular enhanced GFAP expression, d dot-like EMA positivity, e brisk mitotic activity, f tumor necrosis, g high Ki-67 labelling, and h extensive nuclear MYCN expression. Inset in h): Results of two- color fluorescence in situ hybridization demonstrating multiple green signals for the MYCN-locus-probe and 2 red signals for the centromeric control probe. Scale bar = 300 µm in a, 100 µm in b, d, g, h, 200 µm in c, f and 50 µm in e