Table 1.
Neuropsychological test scores in cognitive domains by Lewy body pathology
| Cognitive Domains | Neuropsychological Tests |
LB Pathology | p-value | |
|---|---|---|---|---|
| Not
present n=179 mean, SD |
Present n=98 mean, SD |
|||
| Episodic Memory | Word list I – immediate | 13.8 (6.1) | 11.7 (7.3) | 0.012 |
| Word List II – delayed | 3.4 (2.8) | 2.8 (2.9) | 0.132 | |
| Word List III – recognition | 8.0 (3.1) | 6.9 (3.5) | 0.009 | |
| East Boston Story – immediate | 7.6 (3.4) | 5.9 (4.0) | <0.001 | |
| East Boston Story – delayed recall | 6.5 (4.2) | 4.9 (4.4) | 0.002 | |
| Logical memory Ia | 9.2 (5.8) | 6.9 (5.7) | <0.001 | |
| Logical memory IIa | 7.6 (6.0) | 5.3 (5.4) | <0.001 | |
| Semantic Memory | Boston Naming | 12.9 (2.6) | 11.2 (4.5) | <0.001 |
| Category fluency | 22.1 (10.9) | 19.6 (13.4) | 0.115 | |
| Reading test NART | 7.6 (2.6) | 6.5 (3.3) | 0.003 | |
| Working Memory | Digits forwards | 7.1 (2.6) | 6.1 (3.1) | 0.004 |
| Digits Backwards | 4.9 (2.4) | 4.3 (2.6) | 0.034 | |
| Digital Ordering | 6.0 (2.1) | 4.9 (2.7) | 0.002 | |
| Perceptual Speed | Symbol Digit Modalities | 25.5 (14.3) | 19.8 (16.2) | 0.003 |
| Number comparison | 18.0 (8.7) | 15.6 (9.2) | 0.034 | |
| Stroop – Word Reading | 35.4 (15.0) | 32.8 (15.4) | 0.178 | |
| Stroop – Color Naming | 11.3 (7.3) | 10.0 (7.9) | 0.191 | |
| Visuospatial Ability | Line Orientation | 8.9 (3.7) | 8.1 (4.1) | 0.113 |
| Progressive matrices | 10.0 (3.4) | 9.3 (3.7) | 0.084 | |
p-value derived from t-test