Table 2.
Frequency of Lewy bodies by region and stage in 280 subjects
| Brain and brainstem regions | Regional Frequency of LBs |
Revised LB Stages | |||
|---|---|---|---|---|---|
| No LBs (n=179) |
LBs n,
% (n=101) |
Stage I Olfactory and IX/XMNuc (n=14), n, % |
Stage 2 Limbic and Brainstem (n=40), n, % |
Stage
3 Neocortical (n=47) n, % |
|
| Olfactory bulb and tract | 0 | 86 (85.1) | 10 (71.4) | 33 (82.5) | 43 (91.5) |
| Dorsal motor nucleus of vagus | 0 | 53 (52.5) | 7 (50.0) | 9 (22.5) | 37 (78.7) |
| Nucleus gigantocellularis | 0 | 44 (43.6) | 10 (25.0) | 34 (72.3) | |
| Locus ceruleus | 0 | 38 (37.6) | 9 (22.5) | 29 (61.7) | |
| Pedunculopontine nucleus | 0 | 36 (35.6) | 5 (12.5) | 31 (66.0) | |
| Substantia nigra | 0 | 59 (58.4) | 18 (45.0) | 41 (87.2) | |
| Amygdala | 0 | 74 (73.3) | 30 (75.0) | 44 (93.6) | |
| Entorhinal cortex | 0 | 71 (70.3) | 27 (67.5) | 44 (93.6) | |
| Midtemporal cortex | 0 | 42 (41.6) | 42 (89.4) | ||
| Midfrontal cortex | 0 | 29 (28.7) | 29 (61.7) | ||
| Inferior parietal cortex | 0 | 29 (28.7) | 29 (61.7) | ||
| Motor cortex | 0 | 32 (31.7) | 32 (68.1) | ||
| Heschl’s cortex | 0 | 22 (21.8) | 22 (46.8) | ||