Figure 3.

Case 2, pathologic findings. A) Gross examination of the resected thigh metastasis shows a well-demarcated, soft, red-white ovoid mass within skeletal muscle that focally erodes the adjacent cortex of the femur. B) On low power, the neoplastic cells are arranged in small groups with a delicate background vasculature and foci of myxoid stroma (100x, H&E). A high-power image shows a proliferation of cytologically uniform small cells with round-to-ovoid nuclei, dispersed chromatin, and small nucleoli with variably distinct cell borders (400x, H&E).