Figure10.

(A-C) Microglia/macrophage (IBA-1). The presence of implants elicited increased microglia and macrophage activity (IBA-1 intensity) at the probe vicinity with no statistical difference between the coated and the control probes. (D-F) M1-like macrophage. iNOS positive iba-1 cells showed higher aggregation around both types of implant. However, the density of these M1-like macrophage significantly reduced within the 0-25 μm bin for iSODm coated implants. *p < 0.05. (G-I) M2-like macrophages. Both implants elicited higher aggregation of M2-like macrophage near the implant with no statistical difference between implant types. n = 14 sections for each implant type; 2 repeated measures for each implant location (n = 7 locations for each implant type across N = 3 animals). Error bars represent standard error of the mean. Scale bars represent 100 μm.