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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Acta Biomater. 2019 Aug 22;99:72–83. doi: 10.1016/j.actbio.2019.08.032

Figure 9.

Figure 9.

(A-C) Blood brain barrier leakage. The presence of electrodes created BBB damage as indicated by higher intensity of IgG near both implants. However, at 0-25 μm away, iSODm coated probes elicited significantly less IgG compared to uncoated controls. ***p < 0.001. n = 16 (control) n = 17 (iSODm) sections for each implant type; 2-3 repeated measures for each implant location (n = 7 locations for each implant type across N = 3 animals). Error bars represent standard error of the mean. Scale bars represent 100 μm.