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. 2019 Nov 12;39(11):BSR20192134. doi: 10.1042/BSR20192134

Table 2. Univariate and multivariate Cox analyses of OS in osteosarcoma.

Variables HR (95% CI) P
Univariate analysis
CXCR3 (low vs. high) 3.01 (1.53–5.92) 0.001
Gender (male vs. female) 0.97 (0.51–1.87) 0.931
Age (≥15.1 vs. <15.1 years) 0.88 (0.47–1.67) 0.7
Metastasis (yes vs. no) 3.81 (1.99–7.29) <0.001
Tumor site (femur vs. tibia) 2.79 (0.96–8.16) 0.061
Tumor region (distal vs. proximal) 2.69 (1.00–7.25) 0.051
Surgery (limb sparing vs. amputation) 1.49 (0.35–6.42) 0.591
Progression (yes vs. no) 1.84 (0.86–3.92) 0.116
Histologic response (poor vs. good) 3.93 (1.16–13.36) 0.028
Multivariate analysis
CXCR3 (low vs. high) 3.26 (1.15–9.24) 0.026
Metastasis (yes vs. no) 4.32 (1.61–11.63) 0.004
Histologic response (poor vs. good) 4.72 (1.22–18.21) 0.024