Table 2. Univariate and multivariate Cox analyses of OS in osteosarcoma.
Variables | HR (95% CI) | P |
---|---|---|
Univariate analysis | ||
CXCR3 (low vs. high) | 3.01 (1.53–5.92) | 0.001 |
Gender (male vs. female) | 0.97 (0.51–1.87) | 0.931 |
Age (≥15.1 vs. <15.1 years) | 0.88 (0.47–1.67) | 0.7 |
Metastasis (yes vs. no) | 3.81 (1.99–7.29) | <0.001 |
Tumor site (femur vs. tibia) | 2.79 (0.96–8.16) | 0.061 |
Tumor region (distal vs. proximal) | 2.69 (1.00–7.25) | 0.051 |
Surgery (limb sparing vs. amputation) | 1.49 (0.35–6.42) | 0.591 |
Progression (yes vs. no) | 1.84 (0.86–3.92) | 0.116 |
Histologic response (poor vs. good) | 3.93 (1.16–13.36) | 0.028 |
Multivariate analysis | ||
CXCR3 (low vs. high) | 3.26 (1.15–9.24) | 0.026 |
Metastasis (yes vs. no) | 4.32 (1.61–11.63) | 0.004 |
Histologic response (poor vs. good) | 4.72 (1.22–18.21) | 0.024 |