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. 2019 Nov 12;39(11):BSR20190966. doi: 10.1042/BSR20190966

Table 3. The roles of lncRNAs in MI/R injury.

LncRNA Models Expression Role
RMRP MI/R in mice and H9c2 cells under hypoxia condition Up Knockdown of RMRP could improve cardiac function and reduce the cell apoptosis in mice hearts exposed to MI/R injury [44]
H19 MI/R in mice and neonatal rat primary cardiomyocytes under OGD/R treatment Up Knockdown of H19 could improve cardiac function and decrease infarct size of mice hearts after MI/R [49]
UCA1 CIR in rat Down Improving cell viability of cardiomyocytes [51]
H9c2 cells under H/R treatment Up Attenuating H/R-induced injury in cardiomyocytes [52]
FTX MI/R in mice Down Inhibiting H2O2-induced apoptosis in cardiomyocytes [56]
AK088388 HL-1 cells under H/R treatment Up Promoting autophagy of cardiomyocytes in HL-1 cells under H/R treatment [57]
HIF1A-AS1 MI/R in mice Up Attenuating cells injury and improving cardiac function in mice during MI/R injury [59]