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. 2019 May 24;127(5):386–424. doi: 10.1111/apm.12934

Table 1.

Selected omics studies on psoriasis (PSO) and atopic dermatitis (AD)

GEO ID Year Dx Focus (# samples) Technology Reference
GSE16161 2009 AD, PSO, NN AD‐LS (9), PSO‐LS (15), NN (9) HG‐U133_Plus_2 277
GSE32924 2011 AD, NN LS (13), NL (12), NN (8) HG‐U133_Plus_2 145
GSE27887 2011 AD UVB, LS, NL, w0/w12, 10 pts. (35) HG‐U133_Plus_2 157
GSE36842 2012 AD, NN Acute/chronic, LS, NL, NN, 10 pts (39) HG‐U133_Plus_2 196
GSE75890 2016 AD, PSO, NN Mild ex‐/intrinsic, AD (14), PSO (9), NN (8) HG 2.1 ST 278
GSE60709 2014 AD, NN

Epidermal shave, LS (12), NL (7), NN (14)

DNA methylation, skin and blood

Illumina HT‐12V3.0

Infinium 27K

223
GSE107361 2018 AD Infants/adults, LS (39), NL (40), NN (29) HG‐U133_Plus_2 212
GSE58558 2014 AD Cyclosporin A, LS, NL, w0/w2/w12 (109) HG‐U133_Plus_2 158
GSE59294 2014 AD Dupilumab, LS, NL, w0/w4 (40) HG‐U133_Plus_2 159
GSE120721 2015 AD, NN LCM, LS (15), NL (15), NN (22), epi/dermis HG‐U133_Plus_2 222
GSE65832 2015 AD RNA‐seq, LS (20), NL (20) Illumina GA IIx 279
GSE81119 2017 ‘AD’ mice Mouse models of inflammation and ‘AD’ (37) MG 1.0 ST 280
NA 2018 AD Tape strip RNA‐seq, LS (11), NL (18), NN (13) Ion Torrent 213
GSE120899 2018 AD Apremilast, LS, NL, w0/w12 (59) HG‐U133_Plus_2 Not published?
GSE99802 2018 AD Fezakinumab, LS, NL, w0/w4/w12 (302) HG‐U133_Plus_2 161
GSE121212 2019 AD, PSO, NN RNA‐seq, AD (27LS, 27NL), PSO (28LS, 27NL), NN (38) Illumina GA 334
GSE14905 2008 PSO, NN LS (33), NL (28), NN (21) HG‐U133_Plus_2 143
GSE13355 2009 PSO, NN LS (58), NL (58), NN (64) HG‐U133_Plus_2 281
GSE31037 2011 PSO, NN miRNA, LS (24), NL (23), NN (20) Illumina GA IIx 282
GSE30999 2012 PSO, NN LS (85), NL (85) HG‐U133_Plus_2 283
GSE26866 2012 PSO LCM, LS (20), NL (17), epi/dermis, HG‐U133_A 2.0 284
GSE11903 2009 PSO Etanercept, LS, NL, w0/1/2/4/12 (89) HG‐U133_Plus_2 149
GSE31652 2012 PSO Ixekizumab, LS, w0/w4 (30) HG‐U133_Plus_2 150
GSE55201 2014 PSO, NN Ixekizumab, blood, LS, NN, w0/w2 (81) HG‐U133_Plus_2 285
GSE51440 2014 PSO Guselkumab, LS, NL, w0/w1/w12 (59) HG‐U133_Plus_PM 152
GSE53552 2014 PSO Brodalumab, LS, w0/w1/w2/wq6 (99) HG‐U133_Plus_2 151
GSE69967 2016 PSO Tofacitinib, LS, NL, d0/1/3/w1/2/4/12 (95) HG‐U133_Plus_2 286, 287
GSE54456 2014 PSO, NN RNA‐seq, LS (92), NN (82) Illumina GA 288
GSE57225 2014 PSO‐AD/ACD PSO (23), AD (10), ECZ (13), NL (16) SurePrint G3 8x60K 289
GSE63741 2016 PSO, AD, other AD‐LS, PSO‐LS, ACD, LP, NN (30 each) PIQOR 2.0 290
GSE80047 2016 PSO, PPP(P) PPP (3), PPPP (6), PSO (10), NN (31) HG‐U133_Plus_PM 291
GSE79704 2017 PSO, GPP, NN GPP‐LS (32), PSO‐LS (12), NN (20) HG 2.1 ST 292
GSE73894 2017 PSO, NN DNA methylation, LS (135), NL (41), NN (62) Infinium 450k 293
GSE115797 2018 PSO DNA methylation, LS (24), NL (24) Infinium 450k 185

ACD, allergic contact eczema; Dx, diagnosis; d, day; epi, epidermis; ECZ, eczema (non‐atopic); GPP, generalized pustular psoriasis; LCM, laser‐capture microdissection; LP, lichen planus; PPP, palmoplantar pustulosis; PPPP (palmoplantar pustular psoriasis); PSO‐AD, patients co‐affected by both PSO and AD; w, week.