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. 2019 Nov 7;17(4):1559325819886766. doi: 10.1177/1559325819886766

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Radiation induces gastric morphological and physiological changes in mouse models. A, Representative H&E staining of normal and irradiated gastric tissues 7 days after radiation. B, Quantification of the thickness of gastric mucosa. C, Electron microscopy analysis of gastric tissues from 6 or 12 Gy X-ray irradiated and nonirradiated mice. Representative images of chief cells and parietal cells are shown. D, Serum levels of pepsinogen A (PGA), pepsinogen C (PGC), and gastrin-17 (G17) were measured by ELISA. *P < .05; **P < .01, compared to the nonirradiated (0 Gy) group. H&E indicates hematoxylin and eosin.