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. 2019 Aug 1;27(6):1438–1450. doi: 10.1111/hsc.12814

Table 3.

Change in outcomesa: T0 to T1, T0 to T2 and T1 to T2

  T0–T1 T0–T2 T1–T2
EQ‐5D‐5L (2017 tariff) (n = 128) (n = 61) (n = 49)
Mean score T0 = 0.51; T1 = 0.67 T0 = 0.54; T2 = 0.69 T1 = 0.67; T2 = 0.69
Difference in mean score 0.15 0.15 −0.02
95% CI 0.12, 0.18 0.097, 0.20 −0.086, 0.03
p value <.001 <.001 .451
Effect sizeb 0.831 0.728 −0.108
EQ‐5D (VAS) (n = 127) (n = 61) (n = 51)
Mean score T0 = 51.58; T1 = 63.39 T0 = 51.00; T2 = 68.77 T1 = 65.02; T2 = 68.24
Difference in mean score 11.81 17.77 3.22
95% CI 8.10, 15.52 11.94, 23.60 −3.49, 9.92
p value <.001 <.001 .340
Effect sizeb 0.559 0.780 0.135
ASCOT SCT‐4 (n = 128) (n = 59) (n = 47)
Mean score T0 = 0.73; T1 = 0.82 T0 = 0.70; T2 = 0.80 T1 = 0.791; T2 = 0.792
Difference in mean score 0.09 0.10 0.002
95% CI 0.06, 0.11 0.05, 0.15 −0.04, 0.04
p value <.001 <.001 .928
Effect sizeb 0.641 0.540 0.013
Barthel Index (n = 96) Barthel Index not collected at T2.
Mean score T0 = 72.4; T1 = 80.1
Difference in mean score 7.71
95% CI 4.03, 11.39
p value .001
Effect sizeb 0.424
NEADL Scale (n = 128) (n = 64) (n = 52)
Mean score T0 = 9.67; T1 = 10.40 T0 = 11.58; T2 = 13.22 T1 = 11.50; T2 = 13.29
Difference in mean score 0.73 1.64 1.79
95% CI −0.06, 1.51 0.17, 3.11 0.55, 3.03
p value .071 .029 .006
Effect sizeb 0.161 0.279 0.401
GHQ‐12 (n = 128) (n = 62) (n = 50)
Mean score T0 = 3.95; T1 = 2.42 T0 = 3.89; T2 = 2.10 T1 = 2.62; T2 = 2.06
Difference in mean score −1.53 −1.79 −0.56
95% CI −1.96, −1.11 −2.46, −1.11 −1.28, 0.16
p value <.001 <.001 .123
Effect sizeb −0.629 −0.67 0.222

Difference in mean scores between time points are presented with corresponding: p‐values, 95% CI and effect size. Mean scores at each time point are also presented.

a

For all measures except GHQ‐12, higher scores = better outcomes. For GHQ‐12, it is the reverse.

b

Cohen's d = (mean2 − mean1)/standard deviation, (d = 0.2 small, d = 0.5 medium, d = 0.8 large).