Table 3.
Factors affecting Helicobacter pylori eradication rates by univariate analysis
| Variables | Success (N = 355) | Failure (N = 60) | P value |
|---|---|---|---|
| Sex, n (male/female) | 162/193 | 32/28 | 0.269 |
| Age, y (mean ± SD) | 47.1 ± 12.7 | 48.2 ± 13.3 | 0.559 |
| Occupation, n (outdoor/indoor worker) | 164/191 | 31/29 | 0.432 |
| BMI, kg/m2 (mean ± SD) | 22.3 ± 3.2 | 21.8 ± 3.4 | 0.259 |
| Residential area, n (urban/town/rural) | 205/63/87 | 36/12/12 | 0.731 |
| Marital status, n (single/married) | 24/331 | 3/57 | 0.609 |
| Education level, n (elementary school and below/middle school/university and above) | 39/167/149 | 9/21/30 | 0.511 |
| Family size, n (<4/≥4 people) | 137/218 | 30/30 | 0.096 |
| Annual income, n (<50 000/≥50 000 CNY) | 198/157 | 35/25 | 0.712 |
| Cigarette smoking, n (yes/no) | 72/283 | 16/44 | 0.263 |
| Alcohol consumption, n (yes/no) | 23/332 | 9/51 | 0.022 |
| History of periodontal disease, n (yes/no) | 98/257 | 21/39 | 0.241 |
| Hygiene of dining place, n (good/poor) | 275/80 | 46/14 | 0.891 |
| Main source of drinking water, n (clean/probably polluted) | 307/48 | 56/4 | 0.138 |
| Drinking untreated water, n (yes/no) | 75/280 | 18/42 | 0.127 |
| 13C‐UBT value, n (Q1/Q2/Q3/Q4)* | 91/83/88/93 | 11/22/16/11 | 0.671 |
| Diagnosis by gastroscopy, n (PU/CNAG/CAG/IM/GED) | 15/180/142/16/2 | 3/27/29/1/0 | 0.623 |
| Treatment with adequate dosage and duration, n (yes/no) | 324/31 | 44/16 | 0.000 |
| Choice of PPI, n (esomeprazole/rabeprazole) | 177/178 | 35/25 | 0.225 |
| Vitamin D serum level, n (<10/≥10 ng/mL) | 33/322 | 13/47 | 0.005 |
Note: *13C‐urea breath test (UBT) values were distributed according to quartile: Q1, P0‐P25; Q2, P25‐P50; Q3, P50‐P75; and Q4, P75‐P100. P25 = 9.8; P50 = 20.3; and P75 = 35.6. Statistically significant values are bold.
Abbreviations: BMI, body mass index; CAG, chronic atrophic gastritis; CNAG, chronic non‐atrophic gastritis; GED, gastric epithelial dysplasia; IM, intestinal metaplasia; PPI, proton pump inhibitor; PU, peptic ulcer; SD, standard deviation.