Figure 1.
Proposed biosynthetic pathways for glycyrrhizin and glucoglycyrrhizin in Glycyrrhiza uralensis. The following terms are used: bAS, β‐amyrin synthase; CYP88D6, β‐amyrin 11‐oxidase; and CYP72A154, 11‐oxo‐β‐amyrin 30‐oxidase. The positions of carbon atoms related to these pathways are indicated on the chemical structure of β‐amyrin. Broken arrows indicate unidentified and expected routes to produce glycyrrhizin and glucoglycyrrhizin in the glycyrrhizin‐producing and ‐deficient (83‐555) strains, respectively.