Table 5.
Transmission of Cache Valley virus reported in vectors and hosts across 10 studies
| Transmission type | Original CVV host | Recipient | Transmission successful? | References |
|---|---|---|---|---|
| Ae | Micea | Yesb | Aitken and Spence (1963) | |
| Vector to host | Aedes sollicitans | Mice: Charles River albino | Yes | Yuill & Thompson, (1970) |
| Aedes taeniorhynchus | Mice: Charles River albino | Yes | Yuill & Thompson (1970) | |
| Aedes vexans | Mice: Charles River CD1 and HA/ICR strain | Yes | Saliba et al. (1973) | |
| Anopheles punctipennis | Mice: Charles River CD1 and HA/ICR strain | Yes | Saliba et al. (1)973 | |
| Anopheles quadrimaculatus | Mice: ICR strain | Yes | Blackmore et al. (1998) | |
| Anopheles quadrimaculatus | Mice: Charles River CD1 and HA/ICR strain | Yes | Saliba et al. (1973) | |
| Coquillettidia perturbans | Mice: ICR strain | Yes | Blackmore et al. (1998) | |
| Coquillettidia perturbans | Rabbit: Sylvilagus floridanus | Yes | Blackmore and Grimstad (2008) | |
| Culiseta inornata | Micea | Yes | Corner et al. (1980) | |
| Culex nigripalpus | Micea | Yesb | Aitken and Spence (1963) | |
| Culex quinquefasciatus | Micea | Yesb | Aitken and Spence (1963) | |
| Ochlerotatus communis | Mice: Charles River CD1 and HA/ICR strain | No | Saliba et al. (1973) | |
| Ochlerotatus serratus | Micea | Yesb | Aitken and Spence (1963) | |
| Ochlerotatus triseriatus | Mice: Charles River CD1 and HA/ICR strain | No | Saliba et al. (1973) | |
| Host to vector | Syrian hamster: Mesocricetus auratus | Coquillettidia perturbans | Yes | Saliba et al. (1973) |
| Micea | Aedes scapularis | Yesb | Aitken and Spence (1963) | |
| Micea | Culiseta inornata | Yes | Corner et al. (1980) | |
| Mice and a feeding devicea | Aedes vexans | Yes | Saliba et al. (1973) | |
| Mice and a feeding devicea | Anopheles punctipennis | Yes | Saliba et al. (1973) | |
| Mice and a feeding devicea | Anopheles quadrimaculatus | Yes | Saliba et al. (1973) | |
| Mice and a feeding devicea | Ochlerotatus communis | No | Saliba et al. (1973) | |
| Mice and a feeding devicea | Ochlerotatus sticticus | Yes | Saliba et al. (1973) | |
| Mice and a feeding devicea | Ochlerotatus triseriatus | No | Saliba et al. (1973) | |
| Rabbit: Sylvilagus floridanus | Coquillettidia perturbans | No | Blackmore and Grimstad (2008) | |
| Vector to vector: transovarial | Aedes albopictus | Aedes albopictus (offspring) | No | Miller (1997) |
| Culex fatigans | Culex fatigans (offspring) | No | Tesh and Gubler (1975) | |
| Culiseta inornata | Culiseta inornata (offspring) | Ye | Corner et al. (1980) | |
| Host to host | Mice: ICR strain | Mice: ICR strain | No | Blackmore (1996) |
| Micea | Mice (offspring) a | Yes | Nowicki (1996) | |
| Humans | Humans (offspring)c | No | Nowicki (1996) |
Some studies investigated more than one mode of transmission (Blackmore et al., 1998; Blackmore & Grimstad, 2008; Corner et al., 1980; Saliba et al., 1973).
a
Species or strain name not specified.
b
Isolate TR 20659 was isolated in Trinidad 1958 and was originally classified as CVV but is now considered to be indistinguishable from BeAR7272 which is a Maguari virus isolate (Downs et al., 1961; Groseth et al., 2017).
c
Prenatal transmission determined by the presence of IgM antibodies to CVV in cord blood.