Table 1.
Properties of discontinuous patterns of network activity in the PL of neonatal control and disease model mice
| Group effect | Control | Saline | DISC1 | Df16 | MIA | DISC1 + MIA | Df16 + MIA | KET | ||
|---|---|---|---|---|---|---|---|---|---|---|
| Occurrence (events/min) | ANOVA, F 7,111 = 4.89; p < 0.001*** | 7.07 ± 1.58 | 8.83 ± 1.53 | 7.07 ± 1.68 | 8.67 ± 1.84; p = 0.01 * | 6.77 ± 1.87 | 7.7 ± 2.59; p = 0.01 * | 7.63 ± 2.13 | 8.05 ± 2.83 | |
| Duration (s) | ANOVA, F 7,111 = 3.77; p < 0.001*** | 3.55 ± 1.62 | 4.06 ± 1.35 | 3.48 ± 1.66 | 3.66 ± 1.34 | 3.77 ± 1.36 | 3.33 ± 1.61 | 3.19 ± 0.54 | 3.22 ± 0.97 | |
| Rel. power (3–8 Hz) | ANOVA, F 7,111 = 4.14; p < 0.001*** | 25.43 ± 7.66 | 17.96 ± 5.58 | 28.88 ± 16.05 | 18.61 ± 4.27; p = 0.022 * | 22.38 ± 4.91 | 16.17 ± 6.39; p = 0.035 * | 18.58 ± 10.47 | 16.74 ± 9.32 | |
| Rel. power (12–30 Hz) | 7.93 ± 3.45 | 6.87 ± 1.71 | 7.65 ± 3.4 | 7.35 ± 2.22 | 7.73 ± 4.1 | 6.15 ± 2.47 | 6.25 ± 1.66 | 6.87 ± 1.26 | ||
| MUA firing rate (spikes/s) | ANOVA, F 7,494 = 3.46; p = 0.001** | LII/III | 0.15 ± 0.48 | 0.19 ± 0.38 | 0.21 ± 0.35 | 0.4 ± 1.01 | 0.08 ± 0.56 | 0.06 ± 0.2; p = 0.008 ** | 0.14 ± 0.33 | 0.1 ± 0.22 |
| LV/VI | 0.22 ± 0.35 | 0.69 ± 0.6 | 0.26 ± 0.27 | 0.46 ± 0.41 | 0.2 ± 0.72 | 0.29 ± 0.37 | 0.17 ± 0.38 | 0.17 ± 0.44 | ||
Data are shown as median ± interquartile range. Corrected p values (Benjamin‐Hochberg) for comparisons between controls and disease groups are listed. Italics indicate statistics of ANOVA for GLM/GLME; Italics and bolds indicate statistics of coefficient testing for GLM/GLME. *p < 0.05, **p < 0.01, ***p < 0.001.