Table 1.
Demographics and characteristics of included patients in validation cohort (n = 192)
| Characteristics | Validation cohort (n = 192), n (%) or median (IQR) |
|---|---|
| Demographics | |
| Age, y | 60.7 (50.8‐69.2) |
| Male gender | 110 (57.3%) |
| Immunocompromised a | 125 (65.1%) |
| Smoking a | 100 (52.1%) |
| Chronic pulmonary disease a | 67 (34.9%) |
| Disease characteristics at presentation | |
| Symptom duration before presentation, d | 3.4 (2.0‐7.0) |
| Confusion a | 17 (8.9%) |
| Heart rate, beats per minute | 100 (88‐115) |
| Ear‐based temperature, °C | 37.8 (37.1‐38.9) |
| Systolic blood pressure, mmHg | 130 (115‐145) |
| Diastolic blood pressure, mmHg | 75 (65‐85) |
| Breathing frequency, breaths per minute | 20 (16‐26) |
| Saturation, % b | 95 (92‐97) |
| Meeting sepsis criteria, qSOFA score ≥2 c | 15 (7.8%) |
| Laboratory findings at presentation | |
| pO2 arterial blood gas, mmHg b | 71 (58‐94) |
| pH arterial blood gas | 7.46 (7.39‐7.50) |
| Hemoglobin, mmol/L | 7.9 (6.8‐8.6) |
| Thrombocytes (×109/L) | 203 (128‐257) |
| Leukocytes (×109/L) | 8.3 (4.7‐12.1) |
| Lymphocytes (×109/L) | 1.3 (0.6‐2.5) |
| Neutrophils (×109/L) | 5.5 (2.5‐9.5) |
| C‐reactive protein (mg/L) | 60 (21‐136) |
| Sodium, mmol/L | 135 (133‐138) |
| Urea, mmol/L | 7.1 (4.8‐10.7) |
| Results from other diagnostics at presentation | |
| Ct value RSV, quantitative RT‐PCR | 29.1 (25.2‐33.8) |
| Lower RTI a | 83 (43.2%) |
| Bacterial coinfection a | 81 (42.2%) |
Abbreviations: Ct, cycle time; IQR, interquartile range; pO2, partial pressure of oxygen; RSV, respiratory syncytial virus; RTI, respiratory tract infection; RT‐PCR, reverse transcription polymerase chain reaction.
a
Table S2 for definitions.
b
Not always clear if taken with or without oxygen replacement therapy.
c
qSOFA criteria: altered mental status (Glasgow Coma Scale <15), respiratory rate ≥22, systolic blood pressure ≤100.