Table 3.
Incidence of AEsa by maximum intensity
| HAE attack | Patients with AE intensity, n (%) | |||
|---|---|---|---|---|
| Mild | Moderate | Severe | Any | |
| Attack 1 (n = 20) | 6 (30.0) | 0 | 2 (10.0)b | 8 (40.0) |
| Attack 2 (n = 12) | 1 (8.3) | 1 (8.3) | 0 | 2 (16.7) |
| Attack 3 (n = 9) | 1 (11.1) | 1 (11.1) | 0 | 2 (22.2) |
| Attack 4 (n = 7) | 2 (28.6) | 1 (14.3) | 0 | 3 (42.9) |
| Attack 5 (n = 6) | 0 | 0 | 0 | 0 |
| Attack 6 (n = 5) | 0 | 0 | 0 | 0 |
| Attack 7 (n = 4) | 0 | 1 (25.0) | 0 | 1 (25.0) |
| Attack 8 (n = 4) | 1 (25.0) | 0 | 0 | 1 (25.0) |
| Attack 9 (n = 3) | 0 | 0 | 0 | 0 |
| Attack 10 (n = 3) | 0 | 1 (33.3) | 0 | 1 (33.3) |
Abbreviations: AE, treatment‐emergent adverse event; HAE, hereditary angioedema.
a
AEs reported >97 d after drug administered were not considered treatment‐emergent.
b
One AE of abdominal pain in one patient and one AE of vomiting in one patient; both AEs were considered unrelated to study drug.