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. 2019 Jun 24;19(7):715–731. doi: 10.1111/papr.12801

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© 2019 The Authors. Pain Practice published by Wiley Periodicals, Inc. on behalf of World Institute of Pain.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Patient disposition. All percentages are based on the number of patients randomized. Efficacy and safety analyses were conducted on all randomized patients who received ≥1 dose of study medication. Efficacy analyses were based on the randomized treatment assignment, while safety analyses were based on the actual treatment received. This explains the minor discrepancies seen between the number of patients analyzed for efficacy and safety in some treatment regimens. IPP, immediate postoperative period.