Table 2.
Total | Asystole | Bradycardia | SRD | HVR | AF | |
---|---|---|---|---|---|---|
Number of episodes in Holter‐ECG | 272 | 3 | 105 | 25 | 41 | 98 |
Number of episodes detected by ICM | 315 | 9 | 108 | 26 | 41 | 131 |
True positive (TP) episodes | 269 | 3 | 105 | 25 | 41 | 95 |
False positive (FP) episodes | 46 | 6a | 3a | 1a | 0 | 36b |
False negative (FN) episodes | 3 | 0 | 0 | 0 | 0 | 3c |
Sensitivity = TP/(TP+FN) | 98.9% | 100% | 100% | 100% | 100% | 96.9% |
Positive predictive value = TP/(TP+FP) | 85.4% | 33.3% | 97.2% | 96.2% | 100% | 72.5% |
Note. The analysis included 82 patients with adjudicated Holter findings and ICM data. For details on evaluation methodology, see Appendix 1.
Due to undersensing.
Due to unstable rhythm caused by ventricular extrasystoles or atrial ectopic activity (mimicking R‐R interval irregularity typical for AF), except for one episode of P‐wave oversensing.
Three episodes of AF were evident in the Holter‐ECG but were not detected by the ICM in a single patient having AF alternating with periods of atrial flutter, resulting in too many pseudo‐regular intervals.
Abbreviations: AF = atrial fibrillation; ECG = electrocardiogram; ICM = insertable cardiac monitor; HVR = high ventricular rate; SRD = sudden ventricular rate drop.