Figure 2.

LPS dose‐dependent leukocyte response. (A) Heatmap plot of the top significant genes (ranked by Cohen's D effect size estimate) representing the transcriptional profile of the responses to LPS doses. Columns depict samples; rows depict gene expression indices. Red denotes overexpression; blue denotes under expression. (B) Ingenuity pathway analysis of genes that showed increased expression (red) and decreased expression (blue) in response to higher doses of LPS. –log (BH)P = negative log10‐transformed BH‐adjusted Fisher exact P value