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. 2019 Oct;60(5):439–448. doi: 10.3325/cmj.2019.60.439

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Copyright © 2019 by the Croatian Medical Journal. All rights reserved.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Administration of adipose-derived mesenchymal stem cells (ADMSCs) improved blood-brain barrier (BBB) condition in brain tissues of rats with middle cerebral artery occlusion (MCAO). (A) Quantitative analysis of Evans blue dye detection of BBB condition. (B) Representative images of immunofluorescence detection of OX-42. (C) Representative images of immunofluorescence detection of ZO-1. (D) Representative images of immunofluorescence detection of ZO-1. Asterisk indicates P < 0.05 vs sham group. Dagger indicates P < 0.05 vs MCAO group. Each assay was replicated six times. DAPI – 4,6-diamino-2-phenyl indole.