Figure 1.
Schematic illustration of the technique to correct chemical shift artifacts and separate multiple compounds in 19F‐MRI. A, PFOB and PFCE at different locations in the image. PFOB has a complex spectrum with several resonances, whereas PFCE has a single resonance. B, Two acquisitions with readout in down‐up and left‐right directions (orange arrows), leading to chemical shift artifacts from the multiple PFOB resonances in vertical and horizontal direction, respectively. C, The FLASH sequence diagrams describing the 2 acquisitions with different readout directions. D, The 2 acquisitions are combined using the algorithm described, showing that PFOB and PFCE are separated and chemical shift artifacts resolved