Table 5. Sensitivity, specificity and area under the curve of the tested case definitions for detection of respiratory syncytial virus through the sentinel influenza surveillance system, by age, Portugal, 2010–2018 (n =6,455 persons).
| Age in years | EU ILI % (95% CI) |
ARI-like % (95% CI) |
One respiratory symptom % (95% CI) |
|---|---|---|---|
| Sensitivity | |||
| 0–4 | 56.5 (34.5–76.8) | 56.5 (34.5–76.8) | 100 (85.2–100) |
| 5–14 | 87.5 (47.3–99.7) | 87.5 (47.3–99.7) | 87.5 (47.3–99.7) |
| 15–64 | 90.7 (83.5–95.4) | 90.7 (83.5–95.4) | 100 (96.6–100) |
| ≥ 65 | 75.6 (60.5–87.1) | 75.6 (60.5–87.1) | 100 (92.1–100) |
| Total | 81.1 (74.7–86.4) | 82.1 (75.9–87.3) | 99.5 (97.1–100) |
| Specificity | |||
| 0–4 | 27.7 (20.7–35.7) | 26.4 (19.5–34.2) | 2.7 (0.7–6.8) |
| 5–14 | 19.2 (16.1–22.7) | 19.1 (15.9–22.5) | 3.3 (2.8–3.8) |
| 15–64 | 20.7 (19.5–21.9) | 20.5 (19.4–21.7) | 3.3 (2.8–3.8) |
| ≥ 65 | 23.8 (21.1–26.8) | 23.1 (20.4–26) | 2.5 (1.6–3.8) |
| Total | 21.1 (20.1–22.1) | 20.8 (19.8–21.9) | 3.1 (2.7–3.6) |
| AUC | |||
| 0–4 | 0.42 (0.31–0.53) | 0.41 (0.30–0.52) | 0.51 (0.50–0.53) |
| 5–14 | 0.53 (0.41–0.66) | 0.53 (0.41–0.66) | 0.45 (0.33–0.58) |
| 15–64 | 0.56 (0.53–0.59) | 0.56 (0.53–0.58) | 0.52 (0.51–0.52) |
| ≥ 65 | 0.50 (0.43–0.56) | 0.49 (0.43–0.56) | 0.51 (0.51–0.52) |
| Total | 0.51 (0.48–0.54) | 0.51 (0.49–0.54) | 0.51 (0.51–0.52) |
ARI: acute respiratory infection; AUC: area under curve; CI: confidence interval; EU: European Union; ILI: influenza-like illness.