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. 2019 Mar 4;9(1):2045894019832226. doi: 10.1177/2045894019832226

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 2. — Barriers to drug repurposing and future directions This figure lists the current barriers to a successful drug repurposing and repositioning including patent, regulatory and organizational hurdles and summarizes future directions and recommendations (modified from Pushpakom et al. Nature Reviews 2018). EU, European Union; US, United States; R&D, Research and Development; NIH-NCATS, National Institute of Health – National Center for Advancing translational Sciences; MRC, Medical Research Council; SPARK, Translational Research Program of Stanford.