Table 3.

Treatment of symptoms in children with Fabry disease

Target	Treatment in children
Underlying disease	ERT
Pain	ERT, anti‐epileptics, tricyclic antidepressants and serotonin‐norepinephrine uptake inhibitors
Pathological proteinuria	ERT, ACE inhibitors or ARBs
Hearing loss	Hearing aids, cochlear implant
Cardiovascular disease prevention	Healthy eating, avoidance or cessation of smoking, management of dyslipidaemia and blood pressure using statins if necessary
Gastrointestinal disturbances	ERT, dietary restrictions, small meals
Psychological problems	Psychological support

Abbreviations: ACE, angiotensin enzyme converting; ARBs, angiotensin receptor blockers; ERT, enzyme replacement therapy.