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. Author manuscript; available in PMC: 2019 Nov 13.
Published in final edited form as: J Cell Physiol. 2018 Mar 25;233(9):7239–7252. doi: 10.1002/jcp.26557

FIGURE 7.

FIGURE 7

Physiologic relevance of residual GSK3 activity in fertilization process. (a) Bar diagrams showing the percent of two-cell stage formation after SB216763 (10 μM) treatment of WT and GSK3α-hetero sperm. Untreated set contained equivalent amount of DMSO used for solubilizing SB216763 in the treated set. **p ≤ 0.01 versus control observations. (b) A set of representative light microscopic image showing the reduced number of two-cell staged embryo; black arrow showing the oocytes that formed two-cell stage