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. Author manuscript; available in PMC: 2019 Nov 13.
Published in final edited form as: J Cell Physiol. 2018 Mar 25;233(9):7239–7252. doi: 10.1002/jcp.26557

TABLE 1.

Effect of different isoform specific PDE antagonists in regulation of intracellular cAMP content in GSK3α knockout spermatozoa

cAMP as % of control
GSK3α+/+β+/+ GSK3α+/−β+/−
Untreated 100.0 100.0
IBMX (0.5 mM) 179.0 358.0
Vinpocetine (100 μM) 110.5 114.4
RS25344 (5 μM) 131 314.7
Papaverine HCl (50 μM) 93 185.2
BC 11–38 (20 μM) 98 164.4

Data represent mean ± SEM of n = 3 for all the values. Percentage values are in comparison to corresponding untreated values of GSK3α+/+β+/+ and GSK3α−/−β+/+.