Table 1.
Description and Comparison of Clinicopathologic and Laboratory Parameters of Patients According to the NLR Level
| Variables | Total (n=307) | NLR <1.9 (n=209) | NLR (n=98) | P value | |
|---|---|---|---|---|---|
| Age | 40.36±9.14 | 40.64±9.41 | 39.76±8.54 | 0.429 | |
| Excised tissue (cm2) | 2.35±0.645 | 2.39±0.625 | 2.25±0.680 | 0.085 | |
| Delivery | <3 | 170 (55.4) | 115 (55) | 55 (56.1) | 0.857 |
| 3 | 137 (44.6) | 94 (45) | 43 (43.9) | ||
| Delivery type | NVD | 228 (74.3) | 156 (74.6) | 72 (73.5) | 0.323 |
| CS | 60 (19.5) | 45 (21.5) | 15 (15.3) | ||
| Smoke | yes | 11 (3.6) | 5 (2.4) | 6 (6.1) | 0.111 |
| no | 296 (96.4) | 204 (97.6) | 92 (93.9) | ||
| Contraception | nothing | 36 (11.7) | 26 (12.4) | 10 (10.2) | 0.093 |
| OCP | 65 (21.2) | 37 (17.7) | 28 (28.6) | ||
| others | 206 (67.1) | 146 (69.9) | 60 (61.2) | ||
| History of genital wart | No | 250 (81.4) | 174 (83.3) | 76 (77.6) | 0.231 |
| yes | 57 (18.6) | 35 (16.7) | 22 (22.4) | ||
| History of genital herpes | No | 303 (98.7) | 207 (99) | 96 (98) | 0.595 |
| yes | 4 (1.3) | 2 (1) | 2 (2) | ||
| Pap smear | Normal | 129 (42) | 91 (43.5) | 38 (38.8) | 0.73 |
| LSIL | 34 (11.1) | 24 (11.5) | 10 (10.2) | ||
| HSIL | 22 (7.2) | 16 (7.7) | 6 (6.1) | ||
| ASCUC | 65 (21.2) | 44 (21.1) | 21 (21.4) | ||
| Inflammatory | 22 (7.2) | 14 (6.7) | 8 (8.2) | ||
| Unknown | 35 (11.4) | 20 (9.6) | 15 (15.3) | ||
| Treatment cause | CIN I | 46 (15) | 28 (13.4) | 18 (18.4) | 0.516 |
| CIN II | 204 (66.4) | 142 (67.9) | 62 (63.3) | ||
| CIN III | 57 (18.6) | 39 (18.7) | 18 (18.4) | ||
| Treatment type | LEEP | 235 (76.5) | 154 (73.7) | 81 (82.7) | 0.084 |
| Cold knife conization | 72 (23.5) | 55 (26.3) | 17 (17.3) | ||
| Margin | involved | 28 (9.1) | 14 (6.7) | 14 (14.3) | 0.031 |
| uninvolved | 279 (90.9) | 195 (93.3) | 84 (85.7) | ||
| Recurrence type | CIN I | 18 (47.4) | 9 (90) | 9 (32.1) | 0.019 |
| CIN II | 17 (44.7) | 1 (10) | 16 (57.1) | ||
| CIN III | 2 (5.3) | 0 (0) | 2 (7.1) | ||
| Carcinoma in situ | 1 (2.6) | 0 (0) | 1 (3.6) | ||
| Hb | 12.32±1.19 | 12.31±1.13 | 12.33±1.31 | 0.882 | |
| MCV | 84.71±8.50 | 84.73±9.05 | 84.67±7.25 | 0.956 | |
| RBC | 4.37±0.473 | 4.33±0.471 | 4.46±0.467 | 0.023 | |
| PLT | 260.16±64.65 | 261.8±61.3 | 256.5±71.43 | 0.509 | |
| WBC | 7263.8±1842.7 | 7093.3±1691.7 | 7627.6±2092.6 | 0.018 | |
| ANC | 4111.1±1389.5 | 3738±1112.7 | 4906.6±1580.1 | <0.001 | |
| AMC | 375.4±200.9 | 377.1±212.9 | 371.9±173.5 | 0.833 | |
| AEC | 183.44±136.3 | 186.4±141.7 | 177.1±124.5 | 0.576 | |
| ALC | 2510.3±725.9 | 2744.8±686.7 | 2012.7±531.8 | <0.001 | |
| PLR | 113.3±46.11 | 101.72±36.38 | 137.8±54.47 | <0.001 | |
| LMR | 9.68±11.14 | 11.05±12.87 | 6.88±5.37 | <0.001 |
Data are represented as frequency (percent) or mean±SD. NVD, natural vaginal delivery; C/S, cesarean section; OCP, oral contraceptive pill; LSIL, low grade squamous intraepithelial neoplasia; HSIL, high grade squamous intraepithelial neoplasia; ASCUS, atypical squamous cell undetermined significant; CIN, cervical intraepithelial neoplasia; LEEP, Loop Electrosurgical Excision Procedure; Hb, hemoglobin concentration; MCV, mean corpuscular volume; RBC, Red blood cell count; PLT, platelet; WBC, white blood cell count; ANC, absolute neutrophil count; AMC, absolute monocyte count; AEC, absolute eosinophil count; ALC, absolute lymphocyte count; PLR, platelet-lymphocyte ratio; LMR, lymphocyte-monocyte ratio; NLR, neutrophil-lymphocyte ratio.