Table 2.
Description and Assessment of Factors Affecting Recurrence of Disease
| Recurrence | unadjusted | adjusted | |||||
|---|---|---|---|---|---|---|---|
| Variable | No (n=269) | Yes (n=38) | P value | OR (95%CI) | P value | OR (95%CI) | |
| Age | 40.95±9.05 | 36.18±8.79 | 0.003 | 0.941 (0.904-0.980) | 0.019 | 0.927 (0.870-0.988) | |
| Excised tissue (cm2) | 2.45±0.0601 | 1.63±0.476 | <0.001 | 0.067 (0.028-0.158) | <0.001 | 0.041 (0.013-0.135) | |
| Delivery number | <3 | 142 (83.5) | 28 (16.51) | 0.015 | 2.50 (1.17-5.36) | 0.001 | 7.01 (2.16-22.76) |
| 3 | 127 (92.7) | 10 (7.3) | - | - | |||
| Delivery type | non | 15 (78.9) | 4 (21.1) | - | |||
| NVD | 203 (89) | 25 (11) | 0.199 | 0.462 (0.142-1.50) | |||
| CS | 51 (85) | 9 (15) | 0.537 | 0.662 (0.178-2.46) | |||
| Smoke | no | 261 (88.2) | 35 (11.8) | - | |||
| yes | 8 (72.7) | 3 (27.3) | 0.142 | 2.80 (0.708-11.04) | |||
| Contraception | nothing | 32 (88.9) | 4 (11.1) | - | |||
| OCP | 56 (86.2) | 9 (13.8) | 0.695 | 1.29 (0.366-4.51) | |||
| others | 181 (87.9) | 25 (12.1) | 0.861 | 1.11 (0.360-3.39) | |||
| History of genital wart | No | 223 (89.2) | 27 (10.8) | - | |||
| yes | 46 (80.7) | 11 (19.3) | 0.083 | 1.98 (0.915-4.26) | |||
| History of genital herpes | No | 267 (88.1) | 36 (11.9) | - | - | ||
| yes | 2 (50) | 2 (50) | 0.049 | 7.42 (1.01-54.29) | 0.104 | 23.16 (0.527-1017) | |
| Pap smear | Normal | 116 (89.9) | 13 (10.1) | - | |||
| LSIL | 32 (94.1) | 2 (5.9) | 0.457 | 0.558 (0.120-2.60) | |||
| HSIL | 17 (77.3) | 5 (22.7) | 0.1 | 2.62 (0.831-8.29) | |||
| ASCUC | 54 (83.1) | 11 (16.9) | 0.176 | 1.82 (0.765-4.32) | |||
| Inflammatory | 18 (81.8) | 4 (18.2) | 0.274 | 1.98 (0.582-6.755) | |||
| Unknown | 32 (91.4) | 3 (8.6) | 0.79 | 0.837 (0.225-3.12) | |||
| Treatment cause | CIN I | 43 (93.5) | 3 (6.5) | - | |||
| CIN II | 177 (86.8) | 27 (13.2) | 0.216 | 2.19 (0.634-7.54) | |||
| CIN III | 49 (86) | 8 (14) | 0.23 | 2.34 (0.584-9.38) | |||
| Treatment type | Cold knife conization | 67 (93.1) | 5 (6.9) | 0.117 | - | ||
| LEEP | 202 (86) | 33 (14) | 2.19 (0.821-5.84) | ||||
| Margin | uninvolved | 251 (90) | 28 (10) | - | - | ||
| involved | 18 (64.3) | 10 (35.7) | <0.001 | 4.98 (2.09-11.84) | 0.013 | 6.70 (1.49-30.04)) | |
| NLR | <1.9 | 199 (95.2) | 10 (4.8) | <0.001 | - | <0.001 | - |
| ≥1.9 | 70 (71.4) | 28 (28.6) | 7.96 (3.68-17.22) | 8.49 (2.78-25.93) | |||
| Hb | 12.36±1.14 | 12.04±1.45 | 0.132 | 0.806 (0.608-1.07) | |||
| MCV | 84.99±7.44 | 82.73±13.87 | 0.148 | 0.978 (0.948-1.01) | |||
| RBC | 4.38±0.477 | 4.34±0.0451 | 0.623 | 0.830 (0.395-1.75) | |||
| PLT | 261.9±63.89 | 247.3±69.27 | 0.189 | 0.996 (0.990-1.00) | |||
| WBC | 7168.4±1660.5 | 7939.5±2752.5 | 0.017 | 1.24 (1.04-1.47) | 0.539 | 1.59 (0.364-6.91) | |
| ANC | 3998.2±1192.9 | 4909.7±2216.2 | <0.001 | 1.52 (1.20-1.91) | 0.816 | 1.18 (0.278-5.05) | |
| AMC | 373.4±205.2 | 389.7±169.5 | 0.641 | 1.48 (0.284-7.73) | |||
| AEC | 184±141.1 | 179.3±97.08 | 0.841 | 1 (0.997-1.002) | |||
| ALC | 2579.6±702.2 | 2021.6±711.9 | <0.001 | 0.290 (0.164-0.513) | 0.005 | 0.044 (0.005-0.387) | |
| PLR | 110.1±43.25 | 135.9±58.5 | 0.002 | 1.01 (0.003-1.02) | 0.183 | 0.989 (0.973-1.01) | |
| LMR | 10.13±11.73 | 6.52±4.33 | 0.027 | 0.896 (0.814-0.988) | 0.643 | 0.967 (0.838-1.12) | |
Data are represented as mean ± SD or frequency (percent) whenever it is needed. NVD, natural vaginal delivery; C/S, cesarean section; OCP, oral contraceptive pill; LSIL, low grade squamous intraepithelial neoplasia; HSIL, high grade squamous intraepithelial neoplasia; ASCUS, atypical squamous cell undetermined significant; CIN, cervical intraepithelial neoplasia; LEEP, Loop Electrosurgical Excision Procedure; Hb, hemoglobin concentration; MCV, mean corpuscular volume; RBC, Red blood cell count; PLT, platelet; WBC, white blood cell count; ANC, absolute neutrophil count; AMC, absolute monocyte count; AEC, absolute eosinophil count; ALC, absolute lymphocyte count; PLR, platelet-lymphocyte ratio; LMR, lymphocyte-monocyte ratio; NLR, neutrophil-lymphocyte ratio.